Japanese shares were down on Thursday as investor hopes for monetary easing from the central bank were dashed.
The Bank of Japan held rates unchanged despite pressure to take further action, after cutting interest rates to negative in January failed to provide a much needed boost for the economy.
The Nikkei 225 fell by 2.5% to 16,864.82 points.
Economic data released on Thursday showed a slip back into deflation while industrial production expanded.
In China, the mainland's Shanghai Composite fell 0.7% to 2,933.64 points while Hong Kong's Hang Seng was flat at 21,384.61 .
In Australia, Sydney's ASX/200 rose by 0.4% to 5,206.70.
In South Korea, the benchmark Kospi index lost 0.6% to 2002.30.
Earlier in the morning, the country's tech giant Samsung reported a 12% rise in operating profit, beating analyst forecasts.
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